Download

• Get all pdb files with AlphaMissense score:
• Download PyMOL plugin for coloring:
  Install as a plugin or run as
  run https://alphamissense.hegelab.org/coloram.py. Finally issue the coloram command for coloring the structure.
• You can access individual structures as
  
  • https://alphamissense.hegelab.org/structure/{ID}
    such as https://alphamissense.hegelab.org/structure/cftr_human
    
  • https://alphamissense.hegelab.org/pdb/AF-{UNIPROT_ACC}-F1-AM_v4.pdb
    such as https://alphamissense.hegelab.org/pdb/AF-P13569-F1-AM_v4.pdb
• We provide two API access points:
  • Jumps to the selected residue in the table and focus the structure on this residue:
    https://alphamissense.hegelab.org/hotspot?uid=UNIQID&resi=RESI
    e.g. https://alphamissense.hegelab.org/hotspot?uid=ENST00000003084.10&resi=890
  • Returns json: https://alphamissense.hegelab.org/hotspotapi?uid=UNIQID&resi=RESI
    e.g. https://alphamissense.hegelab.org/hotspot?uid=P13569&resi=890