News
NEW (2025-05-31):
High-confidence REVEL predictions are inserted for a subset of AlphaMissense ambiguous variants - where available.
Please see details in our
preprint.
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DATABASE UPDATE (2025-05-25):
We plan to insert new data into the database next weekend (May 31st). The process will take approximately 8 hours and may temporarily affect the performance of this site.
WARNING (2025-01-13):
A bug in exporting tables as csv files was identified. Specifically, every 1000th line in the mutations table and every 500th line in the hotspot table were merged into a single row during export. This issue could have affected analyses performed using the downloaded CSV files if the number of cells per row was not validated. We have resolved this problem, thanks to
Dave Belmont.
Our paper is online:
Analysis of AlphaMissense data in different protein groups and structural context
Scientific Data 11:495 (2024)
[read]
[cite]
Notes (2024-04-30):
Please note that data for Met1 residues are not provided. Additionally, some proteins not mapped to genomic locations
and the corresponding hotspot table may seem empty. However, data for all a.a. replacements can still be accessed by clicking on the last cell of the table.